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Gene Expression Literature Summary
Assay
Age
In situ reporter (knock in)
10.5 DPC

19 matching records from 19 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Bmp4  bone morphogenetic protein 4   (Synonyms: Bmp2b, Bmp2b1, Bmp2b-1, Bmp-4)
Results  Reference
1J:199300 Bai Y, Wang J, Morikawa Y, Bonilla-Claudio M, Klysik E, Martin JF, Bmp signaling represses Vegfa to promote outflow tract cushion development. Development. 2013 Aug;140(16):3395-402
1J:145964 Chandler KJ, Chandler RL, Mortlock DP, Identification of an ancient Bmp4 mesoderm enhancer located 46 kb from the promoter. Dev Biol. 2009 Mar 15;327(2):590-602
1*J:206541 Engelhard C, Sarsfield S, Merte J, Wang Q, Li P, Beppu H, Kolodkin AL, Sucov HM, Ginty DD, MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons. Elife. 2013;2:e01160
1*J:145756 Goldman DC, Donley N, Christian JL, Genetic interaction between Bmp2 and Bmp4 reveals shared functions during multiple aspects of mouse organogenesis. Mech Dev. 2009 Mar-Apr;126(3-4):117-27
1J:108516 Goldman DC, Hackenmiller R, Nakayama T, Sopory S, Wong C, Kulessa H, Christian JL, Mutation of an upstream cleavage site in the BMP4 prodomain leads to tissue-specific loss of activity. Development. 2006 May;133(10):1933-42
1J:176247 Gordon J, Manley NR, Mechanisms of thymus organogenesis and morphogenesis. Development. 2011 Sep;138(18):3865-78
1J:126770 Hodge LK, Klassen MP, Han BX, Yiu G, Hurrell J, Howell A, Rousseau G, Lemaigre F, Tessier-Lavigne M, Wang F, Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps. Neuron. 2007 Aug 16;55(4):572-86
1J:125109 Huang X, Litingtung Y, Chiang C, Ectopic sonic hedgehog signaling impairs telencephalic dorsal midline development: implication for human holoprosencephaly. Hum Mol Genet. 2007 Jun 15;16(12):1454-68
1*J:159629 Jang CW, Gao L, Dickinson ME, Behringer RR, Bmp4-directed nuclear cyan fluorescent protein provides a tool for live imaging and reveals cellular resolution of Bmp4 expression patterns during embryogenesis. Int J Dev Biol. 2010;54(5):931-8
1J:86001 Jiao K, Kulessa H, Tompkins K, Zhou Y, Batts L, Baldwin HS, Hogan BL, An essential role of Bmp4 in the atrioventricular septation of the mouse heart. Genes Dev. 2003 Oct 1;17(19):2362-7
1J:187837 Jumlongras D, Lachke SA, O'Connell DJ, Aboukhalil A, Li X, Choe SE, Ho JW, Turbe-Doan A, Robertson EA, Olsen BR, Bulyk ML, Amendt BA, Maas RL, An evolutionarily conserved enhancer regulates Bmp4 expression in developing incisor and limb bud. PLoS One. 2012;7(6):e38568
1J:142133 Li Y, Gordon J, Manley NR, Litingtung Y, Chiang C, Bmp4 is required for tracheal formation: a novel mouse model for tracheal agenesis. Dev Biol. 2008 Oct 1;322(1):145-55
1*J:99697 Liu W, Selever J, Murali D, Sun X, Brugger SM, Ma L, Schwartz RJ, Maxson R, Furuta Y, Martin JF, Threshold-specific requirements for Bmp4 in mandibular development. Dev Biol. 2005 Jul 15;283(2):282-93
1J:89237 Liu W, Selever J, Wang D, Lu MF, Moses KA, Schwartz RJ, Martin JF, Bmp4 signaling is required for outflow-tract septation and branchial-arch artery remodeling. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4489-94
1J:97214 Liu W, Sun X, Braut A, Mishina Y, Behringer RR, Mina M, Martin JF, Distinct functions for Bmp signaling in lip and palate fusion in mice. Development. 2005 Mar;132(6):1453-61
1*J:121311 Liu Z, Yu S, Manley NR, Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia. Dev Biol. 2007 May 1;305(1):333-46
1*J:112219 Patel SR, Gordon J, Mahbub F, Blackburn CC, Manley NR, Bmp4 and Noggin expression during early thymus and parathyroid organogenesis. Gene Expr Patterns. 2006 Dec;6(8):794-9
1J:128571 Selever J, Liu W, Lu MF, Behringer RR, Martin JF, Bmp4 in limb bud mesoderm regulates digit pattern by controlling AER development. Dev Biol. 2004 Dec 15;276(2):268-79
1*J:110617 Stottmann RW, Berrong M, Matta K, Choi M, Klingensmith J, The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms. Dev Biol. 2006 Jul 15;295(2):647-63

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory